Primary MCQs-July 2012

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Primary Physiology Black Bank | Primary Pharmacology Black Bank

  • This page contains PHYSIOLOGY MCQs that were on the July 2012 Primary Exam. (For Pharm MCQs - click here).
  • For posting/viewing Pharmacology MCQs go to PharmMCQ:July2012


Primary MCQ papers

Feb06 | Jul06 | Feb07 | Jul07 | Feb08 | Jul08 | Mar09 | Jul09 | Mar10 | Jul10 |

Feb11 | Aug11 | Feb12 | Jul12(Physiol) | Jul12(Pharm) | Feb13(Physiol) | Feb13(Pharm) | Feb13(NewExam) | Sep13 | Feb14 |

Aug14 | Feb15 | Aug15 | Feb16 | Aug16 |

Unclassified so far

All the following statements regarding RBC are true except:

A: does not have mitochondria
B: no nucleus
C: half life 100 days
D. ?

?Something about a substance or condition that cause vasoconstriction

A. Alkalosis
B. Neuropeptide Y
C. Substance P

Basic Physiology

In the formation of DNA (really can't remember but something along these lines)

A. Messenger RNA is called trans
B. Single stranded DNA to DS-DNA
C. Coding parts of DNA (not codons)
D. ..

FE06 Gibbs Donnan effect came up...

The most common effect of cAMP is

A Activate protein kinase A
B Increase Ca++
C Increase DAG

Voltage gated Na+ channels'

A Inactivation gate is closed at rest
B Activation gate opens at -35mV

Fluid and Electrolyte Physiology

During heavy exercise, the sodium content of sweat is: (or was it osmolality of sweat??)

A hypoosmolar to plasma
B hyperosmolar
C isoosmolar
D independent of plasma osmolality (or was it dependent on?)
E dependent on total body water

Not sure about the options, think it was a new question...

Acid Base Physiology

ABG results for a young woman presenting to ED

BE -12(or -13), pH 7.15, pCO2 11mmHg, pO2 110mmHg

This shows:

A Mixed respiratory and metabolic acidosis
B Metabolic acidosis with respiratory compensation
C. ?
D. ?

AD24 [Aug11] Buffering by Hb better than by plasma proteins because (Haemoglobin is an effective buffer because:)

A. Hb has 38 carboxyl residues per globin molecule
B. Hb is present in large concentrations
C. plasma protein pKa near pH of Blood *
D. Deoxyhemoglobin is more acidic than oxyHb
E. Proteins have pKa 6.8
F maybe C. was: Hb's pKa is close to the physiological pH

Respiratory Physiology

Causes of reduced static compliance

A. ageing / elderly
B. pulmonary venous congestion
C. acute asthma
D. emphysema
E. reduced elasticity of tissues

Normal lung volumes of 70kg man

A. TV 350mL
B. RV ....
C. IC 2,000mL - 3,000mL

Pulmonary vascular resistance, increased by

A. alkalosis
B. ?
C. ?

A pCO2 of 200mmHg would lead to what electrolyte abnormality?

A. hyperkalemia
B. ?
C. ?

RE47 [Mar03] [Jul03] [Feb04] [Jul04] [Mar05] The amount of oxygen dissolved in plasma is

A. 0.03ml O2/100ml at PaO2 100mmHg
B. 6ml O2/100ml breathing 100% O2 at 3 atmospheres
C. 6ml O2/100ml breathing room air at 3 atmospheres
D. 0.3ml O2/l breathing room air at 1 atmosphere
E. 6 mlO2/100mls breathing 100% O2

Something about carbamino compounds..

A. Something about carbonic anhydrase..

Cardiovascular Physiology

Lymphatics drain

A: increased proteins from stomach
B: increased lipids from GIT absorption
C. ?

Heart rate is decreased by

A: atrial receptors
B: ventricular receptors
C. ?

Carotid massage decreases SVT

A Decreased SNS stimuli
B increased PNS
C. ?

(repeat) ECG changes in hyperkalaemia

A flattened P waves
B. ?

During isovolumetric contraction..

A aortic pressure falls
B. ?

What happens before/after 2nd heart sound/diastole?

A: v wave
B. ?

Which is true about cardiac muscle cells:

A Each intercalated disc has gap junctions
B Not striated
C It has multiple nuclei per cell

Difference between pressure wave in aorta and pressure wave in radial artery:

A Bigger incisura
B Lower (? higher)systolic pressure
C Lower diastolic pressure
D Lower MAP
E MAP is closer to systolic pressure

Which is true of pressure volume curve of left ventricle:

A end systolic point correlates with contractility
B end systolic point correlates with afterload
C something about diastolic filling curve is an elastance curve
D Diastolic elastance is change in pressure per unit volume

Which is not produced by endothelial cells

B Endothelin
C Thromboxane A2
D Prostacyclin
E Prostaglandin I2 (PGI2)

Something about heart sounds..

A Diastoly occurs just after closure of the aortic valves?
B Systoly occurs just before closure of the mitral valve?

What change is seen with exercise

A. Increased pulse rate
B. Increased blood pressure
C. Increased right atrial pressure
D. Increased stroke volume

Renal Physiology

Sympathetic stim on kidneys...

A decreased gfr
B. ?

Effect of PTH on kidneys: PCT, loop of Henle, collecting duct

A increased ca abs, decreased phosphate
B. ?

GI Physiology

Sinusoids receive the most..

A oxygenated blood
B CYP 450
C. ?

(repeat) GI16 Comparing the small and large intestine

A. bacteria load reduced in small because of gastric acidity and fast transit
B. Main function of bacteria is to break down urea
C. Immune defense is via cell mediated immunity and secretion of IgA

Endocrine and Metabolism

ED14 How many Kcal in one gram Carbohydrate? / The number of kilojoules gained from burning one gram of carbohydrate is: (repeat)

A. 2.8
B. 4.18
C. 5
D. 7
E. 9.1

B is correct (kcals)

ED23 [Mar99] [Jul00] [Feb04] A low respiratory quotient in a septic patient is due to:

A. Increased lactic acid production
B. Fat metabolism
C. Increased ventilation
D. Fever
E. Hypoxaemia

MF05 (repeat) Brown fat:

A. Produces ATP and heat
B. Insulates the great vessels of the neck
C. Is autonomically mediated
D. Extramitochondrial uncoupling of oxidative phosphorylation

Heat loss in a naked man in theatre with 20 deg Celsius ambient temperature is mainly due to:

A. Convection
B. Conduction
C. Radiation


EEG changes from alert to sleep

A. beta, alpha, theta, delta
B. alpha, beta, delta, theta
C. beta, delta, alpha, theta etc
D. etc...

5-HT (i.e. serotonin)

A. amine broken down by MAO
B. 5-HT3 stimulation leads to vomiting

Muscle and NMJ Physiology


Maternal, Fetal and Neonatal Physiology


A. 100x more receptors present during pregnancy
B. Similar action to vasopressin
C. structure of...
D. ?

MF03 [cl] MF03 [cl] [Feb11] [Aug11] [Feb12] In the neonate, closure of the ductus arteriosus occurs due to:

A. Increased prostaglandins
B. Pressure in left atrium exceeds that in right atrium
C. Aortic pressure exceeds pulmonary artery pressure
D. Oxygen mediated smooth muscle constriction
  • . Increased systemic vascular resistance

Clinical Measurement

Barometric pressure is equal to all of the following except

A. 1 BAR
B. 102 cm H20
C. 100 kPa
D. 100 000 N/m2
E. 760mmHg
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