User:Erich gasboy

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Gedday,

My name is Erich Schulz. "Erich gasboy" is the nerdy name I originally gave myself on ebay... I guess I should have ditched it earlier.

Despite a persisting concern that I was going to be the first local Brisbane trainee to fail the finals in some years, and extensive procrastination, I passed the Part 2 on my first sitting in April-May 2007. Yayyyy! Now that I don't have to study (so hard) any more, I've had to dig up a bunch of other activities in order to allow me to continue refining my procrastination skills.

I loved wikis some much I also created gasboys.net. You should visit me over there. Seriously.

I also love a good chat so please leave me a message on my talk page. I especially like to chat about gasboys.net... so if you have any suggestions or questions go ahead and ask... now I have that pesky quiz out of the way I'll put a bit more effort into gasboys.

Currently I am pondering on how to engage others in writing gasboys questions (go you slack gits give it a go).

I have been known to haunt other wikis. The king of all wiki's is, of course wikipedia, so if you're feeling like procrastination... that is the place! I love wiki's. They are great. Good on Kerry (aka User:SysopKB).

I continue to ponder the study I would like to do in obstetrics and other fanciful ideas.

By the way, the FANZCA came through last year... and all I can say to those behind me is that it is well worth the effort.

Best wishes

Erich

PS: Many of my answers are via:

  • Chris (of bulletin board fame) and also
  • Simon Pattullo, Rasa Vencolvas, Kar-Soon Lim (aka SP,RV and KSL)

Contents

Internet and Pubmed tips

Type this (or just a bit of it) after your query to limit your search to English reviews published after 2003:

AND Review[ptyp] AND English[lang] AND 2003:2008[PDat]

for core journals only:

AND jsubsetaim[text]

to search on a MeSH topic that is the focus of the article:

"pain"[MAJR]

To access many journals via the UQ library, put this between immediately before the third slash (it'll only help you if you have a UQ password, but a similar thing probably works for you local library):

.ezproxy.library.uq.edu.au

of sometimes this will work instead, to access a few journals (ICM for one)

.ezproxy.anzca.edu.au

like:

http://home.mdconsult.com.ezproxy.library.uq.edu.au/

Procrastination

Now that I'm past the quiz, my mind is starting to fill with ideas of the study I would like to do.

"Analysis of Variance"[SH] OR "Regression Analysis"[SH]

"randomized controlled trials as topic"[MAJR]


Papers to read:

  1. Pocock SJ, Assmann SE, Enos LE, Kasten LE. Subgroup analysis, covariate adjustment and baseline comparisons in clinical trial reporting: current practice and problems. Stat Med. 2002 Oct 15;21(19):2917-30. PMID 12325108 pdf
  2. Beach ML, Meier P. Choosing covariates in the analysis of clinical trials. Control Clin Trials. 1989 Dec;10(4 Suppl):161S-175S. PMID 2605965 pdf
  3. Wang SJ, Hung HM. Adaptive covariate adjustment in clinical trials. J Biopharm Stat. 2005;15(4):605-11. PMID 16022166 pdf
  4. Kip KE, Hollabaugh K, Marroquin OC, Williams DO. The problem with composite end points in cardiovascular studies: the story of major adverse cardiac events and percutaneous coronary intervention. J Am Coll Cardiol. 2008 Feb 19;51(7):701-7. PMID 18279733
  5. Freemantle N, Calvert M. Composite and surrogate outcomes in randomised controlled trials. BMJ. 2007 Apr 14;334(7597):756-7. PMID 17431231
    "while it is our opinion that composite outcome measures do have a useful role in the evaluation of health technologies, the difficult problem of the appropriate interpretation of composite outcome measures in regulatory policy should be dealt with. This might be achieved by using a corollary (such as a health warning), which makes it clear that on their own the individual components of a composite have not been shown to be affected by the experimental treatment."
  6. Ferreira-González I, Busse JW, et al. Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials. BMJ. 2007 Apr 14;334(7597):786. Epub 2007 Apr 2. PMID 17403713 pdf
  7. Lynch SE, Lavin PT, Genco RJ, Beasley WG, Wisner-Lynch LA. New composite endpoints to assess efficacy in periodontal therapy clinical trials. J Periodontol. 2006 Aug;77(8):1314-22. PMID 16881800
  8. Montori VM, Permanyer-Miralda G, Ferreira-González I, et al. Validity of composite end points in clinical trials. BMJ. 2005 Mar 12;330(7491):594-6. PMID 15761002 pdf
  9. Vickers AJ. Statistical considerations for use of composite health-related quality-of-life scores in randomized trials. Qual Life Res. 2004 May;13(4):717-23. PMID 15129882
  10. Tang DI, Geller NL, Pocock SJ. On the design and analysis of randomized clinical trials with multiple endpoints. Biometrics. 1993 Mar;49(1):23-30. PMID 8513104
  11. Green S, Liu PY, O'Sullivan J. Factorial design considerations. J Clin Oncol. 2002 Aug 15;20(16):3424-30. PMID 12177102
  12. Byth K, Gebski V. Factorial designs: a graphical aid for choosing study designs accounting for interaction. Clin Trials. 2004;1(3):315-25. PMID 16279257
  13. Montgomery AA, Peters TJ, Little P. Design, analysis and presentation of factorial randomised controlled trials. BMC Med Res Methodol. 2003 Nov 24;3:26. PMID 14633287 pdf
  14. Green S, Liu PY, O'Sullivan J. Factorial design considerations. J Clin Oncol. 2002 Aug 15;20(16):3424-30. PMID 12177102 pdf
  15. Stolle DP, Robbennolt JK, Patry M, Penrod SD. Fractional factorial designs for legal psychology. Behav Sci Law. 2002;20(1-2):5-17. Review. PMID 11979488
  16. Green SB. Hypothesis testing in clinical trials. Hematol Oncol Clin North Am. 2000 Aug;14(4):785-95, vii-viii. Review. PMID 10949773
  17. Rockhold FW, Goldberg MR. An approach to the assessment of therapeutic drug interactions with fixed combination drug products. J Biopharm Stat. 1996 Jul;6(3):231-40. Review. PMID 8854228
  18. Green SB, Freedman LS. Early stopping of prevention trials when multiple outcomes are of interest: a discussion. Stat Med. 1994 Jul 15-30;13(13-14):1479-84. PMID 7973227
  19. Byar DP, Herzberg AM, Tan WY. Incomplete factorial designs for randomized clinical trials. Stat Med. 1993 Sep 15;12(17):1629-41. PMID 8235181 pdf
  20. Byar DP. Some statistical considerations for design of cancer prevention trials. Prev Med. 1989 Sep;18(5):688-99. PMID 2694163
  21. Davis BR, Blaufox MD, Hawkins CM, Langford HG, Oberman A, Swencionis C, Wassertheil-Smoller S, Wylie-Rosett J, Zimbaldi N. Trial of antihypertensive interventions and management. Design, methods, and selected baseline results. Control Clin Trials. 1989 Mar;10(1):11-30. PMID 2649308
  22. Patterson HD. Serial factorial design. Biometrika. 1968 Mar;55(1):67-81. No abstract available. PMID 5661055
  23. SHEFFIELD FD. Comment on a distribution-free factorial-design analysis. Psychol Bull. 1957 Sep;54(5):426-8. No abstract available. PMID 13485270


  1. Moher D, Schulz KF, Altman D; CONSORT Group (Consolidated Standards of Reporting Trials) (2001) The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. JAMA. 2001 Apr 18;285(15):1987-91. PMID 11308435
  2. Falcoz PE, Chocron S, Mercier M, Puyraveau M, Etievent JP (2002) Comparison of the Nottingham Health Profile and the 36-item health survey questionnaires in cardiac surgery. Ann Thorac Surg. 2002 Apr;73(4):1222-8. PMID 11996267
  3. Cook DA (2006) Methods to assess performance of models estimating risk of death in intensive care patients: a review. Anaesth Intensive Care. 2006 Apr;34(2):164-75. PMID 16617636
  4. Hariharan S, Zbar A (2006) Risk scoring in perioperative and surgical intensive care patients: a review. Curr Surg. 2006 May-Jun;63(3):226-36. PMID 16757378
  5. Brommels M, Sintonen H (2001) Be generic and specific: quality of life measurement in clinical studies. Ann Med. 2001 Jul;33(5):319-22. PMID 11491189 (not available online via UQ or ANZCA)

Read

  1. Freemantle N, Calvert M, Wood J, Eastaugh J, Griffin C (2003) Composite outcomes in randomized trials: greater precision but with greater uncertainty? JAMA. 2003 May 21;289(19):2554-9. PMID 12759327
  2. Dube L, Granry JC (2003) The therapeutic use of magnesium in anesthesiology, intensive care and emergency medicine: a review. Can J Anaesth. 2003 Aug-Sep;50(7):732-46. PMID 12944451
  3. Bergman S, Feldman LS, Barkun JS (2006) Evaluating surgical outcomes. Surg Clin North Am. 2006 Feb;86(1):129-49, x. PMID 16442425
  4. Kiely JM, Brasel KJ, Weidner KL, Guse CE, Weigelt JA (2006) Predicting quality of life six months after traumatic injury. J Trauma. 2006 Oct;61(4):791-8. PMID 17033542
  5. Kaarlola A, Tallgren M, Pettila V (2006) Long-term survival, quality of life, and quality-adjusted life-years among critically ill elderly patients. Crit Care Med. 2006 Aug;34(8):2120-6. PMID 16763517
  6. Camilleri-Brennan J, Steele RJ (1999) Measurement of quality of life in surgery. J R Coll Surg Edinb. 1999 Aug;44(4):252-9. PMID 10453149
  7. Nemeth G (2006) Health related quality of life outcome instruments. Eur Spine J. 2006 Jan;15 Suppl 1:S44-51. Epub 2005 Dec 1. PMID 16320032
  8. Urbach DR, Harnish JL, McIlroy JH, Streiner DL (2006) A measure of quality of life after abdominal surgery. Qual Life Res. 2006 Aug;15(6):1053-61. PMID 16900285
  9. Urbach DR (2005) Measuring quality of life after surgery. Surg Innov. 2005 Jun;12(2):161-5. PMID 16034507

Questions and papers I should come back to

Questions with content I need to add some gasboys some time

Radha Ravi and Tanya Howell
   Anaesthesia for paediatric ear, nose, and throat surgery
   Contin Educ Anaesth Crit Care Pain 2007 7: 33-37; doi:10.1093/bjaceaccp/mkm004
  • place tube to left for oesaphagectomy
  • reinforced lma ok for tonsils
S Malhotra and V Sodhi
   Anaesthesia for thyroid and parathyroid surgery
   Contin Educ Anaesth Crit Care Pain 2007 7: 55-58; doi:10.1093/bjaceaccp/mkm006

hypocalcaemia:

  • precipitating carpopedal spasm through cuff inflation (Trousseau's sign)
  • facial twitching by tapping over the facial nerve at the parotid gland (Chvostek's sign).


Annie Hunningher and Ian Calder Cervical spine surgery Continuing Education in Anaesthesia, Critical Care & Pain Advance Access published on April 24, 2007. doi:10.1093/bjaceaccp/mkm015

Radiological definitions of cervical spine instability (a) Translation

C1–C2: anterior atlanto-dental interval >5 mm, posterior ADI <13 mm
C2–T1: >3.5 mm between points on adjacent vertebrae

(b) Angulation >11° between vertebrae

These values have been widely used, but there is a poor correlation between radiographic abnormality and neurological symptoms and signs


Criteria for stability after cervical trauma

Unconscious patient:

  • Plain radiographs are inadequate
  • The combination of plain films and CT scans is adequate to diagnose bony and ligamentous instability
  • MR scans are not required for the exclusion of instability

Conscious patient

  • Alert, no distracting injuries
  • No midline pain
  • Normal movement
  • No neurology



AB51 EM52 (will have to draw some.png files)

partially covered

PZ45 PZ53 AB35 SZ19 Insert non-formatted text here

reading list

(these are not earth-shattering, but articles I have read or may come back to if I have time)

  • Murphy EJ (2005) Acute pain management pharmacology for the patient with concurrent renal or hepatic disease. Anaesth Intensive Care. 33(3):311-22 PMID 15973913
    An excellent read for first and second parters!
  • PMID 16916180 Systemic analgesia and co-analgesia
  • Keegan MT, Brown DR (2004) Perioperative antibiotics and practice: little things that make a big difference. Anesthesiol Clin North America. Sep;22(3):473-91. PMID 15325714
  • PMID 15187057 dehydration in kids
  • Harrigan RA, Jones K (2002) ABC of clinical electrocardiography. Conditions affecting the right side of the heart. BMJ. 2002 May 18;324(7347):1201-4 PMID 12016190 http://www.bmj.com/cgi/content/full/324/7347/1201
  • Aders A, Aders H (2005) Anaesthetic adverse incident reports: an Australian study of 1,231 outcomes. Anaesth Intensive Care. 33(3):336-44. PMID 15973916
  • Prielipp RC, Morell RC, Butterworth J (2002) Ulnar nerve injury and perioperative arm positioning. Anesthesiol Clin North America. 20(3):589-603. PMID 12298308
  • Waters JH (2005) Red blood cell recovery and reinfusion. Anesthesiol Clin North America 23(2):283-94, vi. PMID 15922900
  • Karger R, Kretschmer V (2005) Modern concepts of autologous haemotherapy. Transfus Apher Sci. 2005 Apr;32(2):185-96. PMID 15784453
  • Catling S, Joels L (2005) Cell salvage in obstetrics: the time has come. BJOG. 2005 Feb;112(2):131-2 PMID 15663574 [1]
  • Senturk M (2006) New concepts of the management of one-lung ventilation. Curr Opin Anaesthesiol. 19(1):1-4 PMID 16547426
  • Ollerton JE, Parr MJ, Harrison K, Hanrahan B, Sugrue M (2006) Potential cervical spine injury and difficult airway management for emergency intubation of trauma adults in the emergency department--a systematic review. Emerg Med J. 2006 Jan;23(1):3-11. PMID 16373795
  • Coagulation Monitoring Rochon AG - Anesthesiol Clin North America - December 2006; 24(4); 839-856
  • Joe RR, Chen LQ (2003) Anesthesia in the cardiac catheterization lab. Anesthesiol Clin North America. 2003 Sep;21(3):639-51. PMID 14562570
  • Conlay LA (2003) Special concerns in the cardiac catheterization lab. Int Anesthesiol Clin. 2003 Spring;41(2):63-7. PMID 12711914
  • Aitkenhead AR (2005) Injuries associated with anaesthesia. A global perspective. Br J Anaesth. 2005 Jul;95(1):95-109 PMID 15908453
  • Khan KS, Wojdyla D, Say L, Gulmezoglu AM, Van Look PF (2006) WHO analysis of causes of maternal death: a systematic review. Lancet. 2006 Apr 1;367(9516):1066-74. PMID 16581405
  • Malhotra S, Yentis SM (2006) Reports on Confidential Enquiries into Maternal Deaths: management strategies based on trends in maternal cardiac deaths over 30 years. Int J Obstet Anesth. 2006 Jul;15(3):223-6. PMID 16798448
  • Dorges V (2005) Airway management in emergency situations. Best Pract Res Clin Anaesthesiol. 2005 Dec;19(4):699-715. PMID 16408542
  • Levy DM (2006) Emergency Caesarean section: best practice. Anaesthesia. 2006 Aug;61(8):786-91. PMID 16867092
  • Volk ML, Marrero JA. Advances in critical care hepatology. Minerva Anestesiol. 2006 May;72(5):269-81. PMID 16675936
  • American College of Physicians (2006) Risk assessment for and strategies to reduce perioperative pulmonary complications for patients undergoing noncardiothoracic surgery: a guideline from the American College of Physicians. Ann Intern Med. 2006 Apr 18;144(8):575-80. PMID 16618955
  • Deitch EA, Dayal SD (2006) Intensive care unit management of the trauma patient. Crit Care Med. 2006 Sep;34(9):2294-301. PMID 16878037

Interesting articles for Part-Oners

  • Bruhn J, Myles PS, Sneyd R, Struys MM (2006) Depth of anaesthesia monitoring: what's available, what's validated and what's next? Br J Anaesth. 2006 Jul;97(1):85-94. Epub 2006 Jun 2. PMID 16751211
  • Sturgess DJ, Marwick TH, Joyce CJ, Venkatesh B (2006) B-type natriuretic peptide concentrations and myocardial dysfunction in critical illness. Anaesth Intensive Care. 2006 Apr;34(2):151-63 PMID 16617635
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